Establishing research is a priority that relates to the Campbell Medicine mission. Our faculty make contributions to the advancement of medicine through areas such as basic science, clinical science, medical and educational research.
Dr. Alekseev’s research focuses on the investigation of the utility of tNASP as a potential diagnostic marker for PC.
Disease prevention through recognizing the causal or contributing factors has been the basis of my research thus far. The bulk of Dr. Brenseke’s research is rooted in the fetal origins of adult disease which examines how early (e.g., in utero or during the post-natal period) exposures to harmful agents can have long-term consequences. To date, she has focused on nutritional exposures and the impact that a maternal high fat diet has on the growth and development of the offspring, particularly as it relates to bone and metabolic health.
Dr. Foster’s research focuses on how growth and development of the locomotor system can provide insight into the links between form and function in humans and other mammals to explore how these organisms adapt to environmental and ecological challenges.
Research in Dr. Hamrick’s lab focuses on in vivo and in vitro virulence properties of Listeria monocytogenes. To that end we generate targeted bacterial mutants, and assess virulence in models of infection and in tissue culture cells. A new area of interest in the lab involves the development antivirulence compounds as an alternative to antimicrobials and antibiotics.
Dr. Kaprielian’s primary focus is on education, and assessment of various educational modalities. I also have a strong interest in clinical quality improvement and patient safety.
Dr. Kuo’s research focuses on determining the critical infectious diseases issues in the underserved areas of the State of North Carolina, and to identify the preventative opportunities to improve the public health in these areas.
Oxidative and inflammatory stress in degenerative disorders and mechanistically-based chemoprotection.
The impact of undergraduate medical school education on the affective and cognitive empathy. This is a seven-year longitudinal study that looks at changes in empathy for the first four matriculating Campbell Medicine classes.
Dr. Penning’s research includes the impact of insulin levels and insulin resistance on the tendency to gain weight and ability to lose weight, effect of personalized coaching on tobacco cessation quit rates and development of obesity curriculum for medical school education.
Starting in the last academic year, Dr. Reisner began research involving the detection of driver mutations in skin lesions present on cadaveric samples used by Campell med students. We have successfully determined a technique allowing for DNA extraction from cadaveric skin and have sequenced a control and lesional skin sample for several hundred genes involved in neoplastic disease. Although analysis is in progress, the single gene level sequencing was successful and the driver mutation was not detected. (There was about a 50% prior probability of detection in the initial samples.) We intend to further analyze these results and submit a proposal for additional funding.
Dr. Terreberry’s research focuses on curriculum development: the use of technology in the teaching of anatomy.
Dr. Traore’s research entails the reproductive toxicology, aging and cancer drug development. Currently, his work is directed toward understanding the role of reactive oxygen species in the mechanism of toxicity associated with exposures to environmental chemicals and pharmaceutical drugs.
Dr. Zhu focuses on oxidative stress in the pathogenesis of diseases and intervention of the disease processes by up-regulating the antioxidative system.